个人简历

1988.9-1992.7 安徽师范大学化学系学习获（理学）学士学位

1999.9-2004.6 中国科学技术大学化学系学习或（理学）博士学位

2004.7-2006.10 Suntory Institute for Bioorganic Research, Osaka, Japan从事博士后研究

主要研究领域、方向

课题组主页—http://121.251.19.227/_s181/main.psp

硕士生招生专业：化学工程与技术(学术型)、化学（学术型）、化学工程(专业型)

博士生招生专业：材料学、材料化学工程（学术型）；能源动力（工程博士）

目前的研究方向：有机合成及不对称催化、精细化学品如有机新材料、医药、香料等化工产品的合成与产业化研究。

主讲本科生课程：有机合成；精细化学品化学

研究成果（代表性成果）

1）L-薄荷醇及其系列衍生物的制备及工业化技术；

2）香料、医药、农药等精细化学品的制备及产业化；

3）特种乙烯基硅油的产业化技术

目前承担科研项目

目前承担科研项目：

1）科工局重大专项1项

2）企业委托项目2项

主持承担及完成的主要项目：

主持：应用化学专业综合改革试点    (2015.01-2017.12)

主持：紫罗兰酮潜香物的合成及应用 (2016.09-2018.06)

主持：烟用微胶囊制备技术研究与开发 (2016.09-2017.03)

主持：医药中间体—杂环戊烷基甲酸-L-薄荷脂的合成关键技术研究 (2016.01-2018.12)

主持：紫罗兰酮潜香物的合成及应用（2017.05-2020.12）

获奖及专利情况

授权专利：
[1] 阿司匹林精氨酸盐的制备方法 专利号：ZL 200910116234.1
[2] 一种废聚丙烯丝束嘴棒下脚料中聚丙烯回收的方法 专利号：ZL 200910117141.0
[3] 一种(S)-异丙甲草胺的合成方法 专利号：201410653105.7
[4] 一类双亚砜化合物及其合成方法与应用 专利号：ZL201510623401.7

著作论文（代表作）

  教材：

      1）主编《有机合成化学》，化学工业出版社，2016.1

      2）副主编：《有机合成化学习题集》，合肥工业大学出版社，2021.4

著作论文（代表作）：

[1] Wenbing Wang, Min Chen, Wenmin Pang, Yougui Li*, Chen Zou*, and Changle Chen*. Palladium-Catalyzed Synthesis of Norbornene-Based Polar Functionalized Polyolefin Elastomers. Macromolecules 2021, 54, 3197−3203.

[2] Xiang Wu,* Shuang-Gui Song, Xin Zhang,Yan-Ming Fu, Cheng-Feng Zhu, and You-Gui Li*. Copper-Catalyzed Direct Oxidative α-Alkoxylation of 4-Isochromanones. Eur. J. Org. Chem. 2021, 2436–2439.

[3] Qitong Wu,  Wenbing Wang, Guoyong Xu, Wenmin Pang, Yougui Li*, Chen Tan, Fuzhou Wang*. Bulky iminophosphine‐based nickel and palladium catalysts bearing 2,6-dibenzhydryl groups for ethylene oligo/polymerization. Appl Organometal Chem. 2020.

[4] Zhu, C.*，Tang, H，Yang, K，Wu, X，Luo, Y，Li, Y.*. A urea-containing metal-organic framework as a multifunctional heterogeneous hydrogen bond-donating catalyst. Catalysis Communications 2020,135, 105837.

[5] Xiang Wu*, Lang-Lang Zheng, Li-Ping Zhao, Cheng-Feng Zhu, You-Gui Li*. Gold-catalyzed cyclization of 1-(2'-azidoaryl) propynols: synthesis of polysubstituted 4-quinolones. ChemicalCommunications,2019,55, 14769-14772.

[6] Yong-Shuang Huang, Shuang-Gui Song,You-Gui Li, Xiang Wu*. Enantioselective γ-Alkylation of α,β-Unsaturated Aldehydes Using New Cinchona-Based Primary Amine Catalyst. European Journal of Organic Chemistry,2019, 6838-6841.

[7] Xiang Wu*, Hai-Jie Zhu, Shi-Bao Zhao, Yun-Fei Luo, You-Gui Li. An Asymmetric Dehydrogenative Diets-Alder Reaction for the Synthesis of Chiral Tetrahydrocarbazole Derivatives. Organic Letters, 2018, 20, 32-35.

[8] Fang Jun，Yougui*，Chen Changle*. Synthesis of polyolefin elastomers from unsymmetrical -diimine nickel catalyzed olefin polymerization. Polymer Chemistry, 2018, 9(30), 4143-4149.

[9] Zhu, C., Luan, J., Wu, X., Li, Y., Luo, Y.*. A Rhodium-Catalyzed [3 + 2] Annulation of General Aromatic Aldimines/Ketimines and N-Substituted Maleimides. Organic Letters 2018, 20(18), 5960-5963.

[10] Xiang Wu*, Hai-Jun Wang, Yong-Shuang Huang, Li*. Intramolecular [2 + 2] Cycloadditions of Alkyl(phenylthio)ketenes: Total Synthesis of (+)-Sphaerodiol. Organic Letters, 2018, 20, 1871-1874.

[11] Xiang Wu*, Shi-Bao Zhao, Lang-Lang Zheng, You-Gui Li*. Oxidative Asymmetric Formal Aza-Diels-Alder Reactions of Tetrahydro-beta-carboline with Enones in the Synthesis of Indoloquinolizidine-2-ones. Molecules, 2018, 23, 2228.

[12] Zhu, C.*; Mao, Q.; Li, C.; Li, Y. A readily available urea based MOF that act as a highly active heterogeneous catalyst for Friedel-Crafts reaction of indoles and nitrostryenes. Catal. Commun., 2018, 104, 123-127.

[13] Wang Hai-Jun, Zhu Cheng-Feng, Luo Yun-Fei, Li You-Gui, Wu Xiang*. Pd/C-Catalyzed Dehydrogenative [3+2] Cycloaddition for the Synthesis of Functionalized Tropanes. Eur. J. Org. Chem. 2018,2018, 5456-5459.

[14] Deng Weili; Li You Gui; Bao Hongli. Iron-Catalyzed Carboiodination of Alkynes. Synthesis, 2018, 50(15), 2974-2980.

[15] You-Gui Li,* Li Li, Ming-Yue Yang, Gang He, and Eric Assen B. Kantchev*, A Bulky Disulfoxide Ligand for Pd-Catalyzed Oxidative Allylic C−H Amination with 2,2,2-Trichloroethyl Tosyl Carbamate. J. Org. Chem., 2017, 82, 4907-4917.

[16] Ya-Ling Zou, Zhen-Yu Wang, Yin-Mao Feng, You-Gui Li*. Solvent and Base in One: Tetra-n-butylammonium Acetate as a Multi-Purpose Ionic Liquid Medium for Ru-Catalyzed Directed Mono- and Di-o-C-H Arylation Reactions,  Eur. J. Org. Chem., 2017, 6274-6282.

[17]You-Gui Li, Zhen-Yu Wang,Ya-Ling Zou, Eric Assen B. Kantchev*, Bulky Phosphane Ligand for Monoselective Ruthenium-Catalyzed, Directed O-C–H Arylation with Challenging Aryl Chlorides. Synlett., 2017, 28, 499-503.

[18]Chengfeng Zhu* , Yunfei Wang, Qing qing Mao, You gui Li and Changle Chen*. Two 8-Hydroxyquinolinate Based Supramolecular Coordination Compounds: Synthesis, Structures and Spectral Properties. Materials, 2017, 10(3), 313.